BPK-21

Modify Date: 2024-01-09 18:28:36

BPK-21 Structure
BPK-21 structure
Common Name BPK-21
CAS Number 2305052-77-9 Molecular Weight 466.28
Density N/A Boiling Point N/A
Molecular Formula C23H16Cl2F3NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BPK-21


BPK-21, an active acrylamide, suppresses T cell activation through blockade of ERCC3 function. BPK-21 specifically targets C342 in the helicase ERCC3[1].

 Names

Name BPK-21

 BPK-21 Biological Activity

Description BPK-21, an active acrylamide, suppresses T cell activation through blockade of ERCC3 function. BPK-21 specifically targets C342 in the helicase ERCC3[1].
Related Catalog
In Vitro BPK-21 (20 μM) significantly impaired T cellactivation[1]. BPK-21 likely suppresses T cell activation through blockadeof ERCC3 function, which may in turn act downstream or sepa-rately from pathways involved in NFAT and NF-kB activation[1].
References

[1]. Ekaterina V Vinogradova, et al. An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29.

 Chemical & Physical Properties

Molecular Formula C23H16Cl2F3NO2
Molecular Weight 466.28
Top Suppliers:I want be here


Get all suppliers and price by the below link:

BPK-21 suppliers

BPK-21 price