Name | BPK-21 |
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Description | BPK-21, an active acrylamide, suppresses T cell activation through blockade of ERCC3 function. BPK-21 specifically targets C342 in the helicase ERCC3[1]. |
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Related Catalog | |
In Vitro | BPK-21 (20 μM) significantly impaired T cellactivation[1]. BPK-21 likely suppresses T cell activation through blockadeof ERCC3 function, which may in turn act downstream or sepa-rately from pathways involved in NFAT and NF-kB activation[1]. |
References |
Molecular Formula | C23H16Cl2F3NO2 |
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Molecular Weight | 466.28 |