IU1-248

Modify Date: 2024-01-10 16:33:26

IU1-248 Structure
IU1-248 structure
Common Name IU1-248
CAS Number 2307472-03-1 Molecular Weight 337.42
Density N/A Boiling Point N/A
Molecular Formula C20H23N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IU1-248


IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.

 Names

Name IU1-248

 IU1-248 Biological Activity

Description IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.
Related Catalog
In Vitro IU1-248 exhibits an IC50 value of 0.83 μM toward USP14, which is comparable to that of IU1-47 (IC50=0.68 μM) and 10-fold more potent than that of IU1 (IC50=12.25 μM)[1].
References

[1]. Yiwei Wang, et al. Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res. 2018 Dec;28(12):1186-1194.

 Chemical & Physical Properties

Molecular Formula C20H23N3O2
Molecular Weight 337.42
Storage condition 2-8°C
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