E3 ligase Ligand-Linker Conjugates 49

Modify Date: 2024-01-12 18:22:28

E3 ligase Ligand-Linker Conjugates 49 structure	Common Name	E3 ligase Ligand-Linker Conjugates 49
	CAS Number	2351103-63-2	Molecular Weight	648.70
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₄₄N₄O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of E3 ligase Ligand-Linker Conjugates 49

E3 ligase Ligand-Linker Conjugates 49 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 49 can be used to design PROTAC degrader.

Name	E3 ligase Ligand-Linker Conjugates 49

Description	E3 ligase Ligand-Linker Conjugates 49 incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 49 can be used to design PROTAC degrader.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.

Molecular Formula	C₃₁H₄₄N₄O₁₁
Molecular Weight	648.70