SPL-410

Modify Date: 2024-01-10 12:14:59

SPL-410 Structure
SPL-410 structure
Common Name SPL-410
CAS Number 2351886-00-3 Molecular Weight 500.57
Density N/A Boiling Point N/A
Molecular Formula C24H31F3N2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SPL-410


SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1].

 Names

Name SPL-410

 SPL-410 Biological Activity

Description SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1].
Related Catalog
Target

IC50: 9 nM (SPPL2a)[1].

References

[1]. Velcicky J, et al. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. ACS Med Chem Lett. 2019 May 23;10(6):887-892.

 Chemical & Physical Properties

Molecular Formula C24H31F3N2O4S
Molecular Weight 500.57