Bis-(m-PEG8-amido)-hexanoic acid

Modify Date: 2024-01-08 11:00:50

Bis-(m-PEG8-amido)-hexanoic acid structure	Common Name	Bis-(m-PEG8-amido)-hexanoic acid
	CAS Number	2353409-77-3	Molecular Weight	967.10
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₂H₈₂N₂O₂₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Bis-(m-PEG8-amido)-hexanoic acid

Bis-(m-PEG8-amido)-hexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-(m-PEG8-amido)-hexanoic acid

Description	Bis-(m-PEG8-amido)-hexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₂H₈₂N₂O₂₂
Molecular Weight	967.10