Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bis-(m-PEG4)-amidohexanoic acid
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

2353409-74-0

2353409-74-0 structure

2353409-74-0 structure

Name: Bis-(m-PEG4)-amidohexanoic acid
Chemical Name: Bis-(m-PEG4)-amidohexanoic acid
CAS Number: 2353409-74-0
Molecular Formula: C₂₆H₅₀N₂O₁₂
Molecular Weight: 582.68
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:48:13
Modify Date: 2024-01-07 17:30:06
Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-(m-PEG4)-amidohexanoic acid

Description	Bis-(m-PEG4)-amidohexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₅₀N₂O₁₂
Molecular Weight	582.68