1964503-35-2

1964503-35-2 structure
1964503-35-2 structure
  • Name: N-Biotin-N-bis(PEG4-acid)
  • Chemical Name: N-Biotin-N-bis(PEG4-acid)
  • CAS Number: 1964503-35-2
  • Molecular Formula: C32H57N3O14S
  • Molecular Weight: 739.87
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 16:12:07
  • Modify Date: 2024-01-10 10:47:18
  • N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Biotin-N-bis(PEG4-acid)
Synonyms MFCD30458057
Description N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C32H57N3O14S
Molecular Weight 739.87