Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bis-(m-PEG8-amido)-hexanoic acid
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

2353409-77-3

2353409-77-3 structure

2353409-77-3 structure

Name: Bis-(m-PEG8-amido)-hexanoic acid
Chemical Name: Bis-(m-PEG8-amido)-hexanoic acid
CAS Number: 2353409-77-3
Molecular Formula: C₄₂H₈₂N₂O₂₂
Molecular Weight: 967.10
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 10:22:12
Modify Date: 2024-01-08 11:00:50
Bis-(m-PEG8-amido)-hexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-(m-PEG8-amido)-hexanoic acid

Description	Bis-(m-PEG8-amido)-hexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₂H₈₂N₂O₂₂
Molecular Weight	967.10