Diketone-PEG4-PFP ester

Modify Date: 2024-01-11 18:25:08

Diketone-PEG4-PFP ester Structure
Diketone-PEG4-PFP ester structure
Common Name Diketone-PEG4-PFP ester
CAS Number 2353409-84-2 Molecular Weight 647.58
Density N/A Boiling Point N/A
Molecular Formula C30H34F5NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Diketone-PEG4-PFP ester


Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diketone-PEG4-PFP ester

 Diketone-PEG4-PFP ester Biological Activity

Description Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C30H34F5NO9
Molecular Weight 647.58