Tubulin inhibitor 26

Modify Date: 2024-01-11 13:38:05

Tubulin inhibitor 26 structure	Common Name	Tubulin inhibitor 26
	CAS Number	2379241-70-8	Molecular Weight	313.35
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₉N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tubulin inhibitor 26

Tubulin inhibitor 26 (compound 3c) is a potent inhibitor of tubulin. Tubulin inhibitor 26 is an indazole derivative compound. Tubulin inhibitor 26 shows noteworthy low nanomolar potency against HepG2, HCT116, SW620, HT29 and A549 cancer cell lines. Tubulin inhibitor 26 arrests tumor cell in G2/M phase and induced cell apoptosis. Tubulin inhibitor 26 suppresses tumor growth in vivo without affecting the mice body weight[1].

Name	Tubulin inhibitor 26

Description	Tubulin inhibitor 26 (compound 3c) is a potent inhibitor of tubulin. Tubulin inhibitor 26 is an indazole derivative compound. Tubulin inhibitor 26 shows noteworthy low nanomolar potency against HepG2, HCT116, SW620, HT29 and A549 cancer cell lines. Tubulin inhibitor 26 arrests tumor cell in G2/M phase and induced cell apoptosis. Tubulin inhibitor 26 suppresses tumor growth in vivo without affecting the mice body weight[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Cui YJ, et al. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo. Eur J Med Chem. 2020;187:111968

Molecular Formula	C₁₇H₁₉N₃O₃
Molecular Weight	313.35

Tubulin inhibitor 26

Use of Tubulin inhibitor 26

Names

Tubulin inhibitor 26 Biological Activity

Chemical & Physical Properties