2379241-70-8

2379241-70-8 structure
2379241-70-8 structure
  • Name: Tubulin inhibitor 26
  • Chemical Name: Tubulin inhibitor 26
  • CAS Number: 2379241-70-8
  • Molecular Formula: C17H19N3O3
  • Molecular Weight: 313.35
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
  • Create Date: 2022-06-26 18:00:31
  • Modify Date: 2024-01-11 13:38:05
  • Tubulin inhibitor 26 (compound 3c) is a potent inhibitor of tubulin. Tubulin inhibitor 26 is an indazole derivative compound. Tubulin inhibitor 26 shows noteworthy low nanomolar potency against HepG2, HCT116, SW620, HT29 and A549 cancer cell lines. Tubulin inhibitor 26 arrests tumor cell in G2/M phase and induced cell apoptosis. Tubulin inhibitor 26 suppresses tumor growth in vivo without affecting the mice body weight[1].

Name Tubulin inhibitor 26
Description Tubulin inhibitor 26 (compound 3c) is a potent inhibitor of tubulin. Tubulin inhibitor 26 is an indazole derivative compound. Tubulin inhibitor 26 shows noteworthy low nanomolar potency against HepG2, HCT116, SW620, HT29 and A549 cancer cell lines. Tubulin inhibitor 26 arrests tumor cell in G2/M phase and induced cell apoptosis. Tubulin inhibitor 26 suppresses tumor growth in vivo without affecting the mice body weight[1].
Related Catalog
References

[1]. Cui YJ, et al. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo. Eur J Med Chem. 2020;187:111968

Molecular Formula C17H19N3O3
Molecular Weight 313.35