SK3 Channel-IN-1

Modify Date: 2024-01-17 20:30:08

SK3 Channel-IN-1 Structure
SK3 Channel-IN-1 structure
Common Name SK3 Channel-IN-1
CAS Number 2396571-04-1 Molecular Weight 379.66
Density N/A Boiling Point N/A
Molecular Formula C25H49NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SK3 Channel-IN-1


SK3 Channel-IN-1 (compound 7a) is a potent and specific SK3 channel modulator. SK3 Channel-IN-1 has efficient effect on breast cancer MDA-MB-435 cell migration while exhibiting low cytotoxicity in other cell lines. SK3 Channel-IN-1 can modulate ion channels’activity in cancer[1].

 Names

Name SK3 Channel-IN-1

 SK3 Channel-IN-1 Biological Activity

Description SK3 Channel-IN-1 (compound 7a) is a potent and specific SK3 channel modulator. SK3 Channel-IN-1 has efficient effect on breast cancer MDA-MB-435 cell migration while exhibiting low cytotoxicity in other cell lines. SK3 Channel-IN-1 can modulate ion channels’activity in cancer[1].
Related Catalog
Target

IC50: 16 μM in CaCo-2[1]

References

[1]. Kouba S, et al. Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity. Eur J Med Chem. 2020;186:111854.

 Chemical & Physical Properties

Molecular Formula C25H49NO
Molecular Weight 379.66