2396571-04-1

2396571-04-1 structure

Name: SK3 Channel-IN-1
Chemical Name: SK3 Channel-IN-1
CAS Number: 2396571-04-1
Molecular Formula: C₂₅H₄₉NO
Molecular Weight: 379.66
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2022-07-30 08:53:49
Modify Date: 2024-01-17 20:30:08
SK3 Channel-IN-1 (compound 7a) is a potent and specific SK3 channel modulator. SK3 Channel-IN-1 has efficient effect on breast cancer MDA-MB-435 cell migration while exhibiting low cytotoxicity in other cell lines. SK3 Channel-IN-1 can modulate ion channels’activity in cancer[1].

Name	SK3 Channel-IN-1

Description	SK3 Channel-IN-1 (compound 7a) is a potent and specific SK3 channel modulator. SK3 Channel-IN-1 has efficient effect on breast cancer MDA-MB-435 cell migration while exhibiting low cytotoxicity in other cell lines. SK3 Channel-IN-1 can modulate ion channels’activity in cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	IC50: 16 μM in CaCo-2[1]
References	[1]. Kouba S, et al. Lipidic synthetic alkaloids as SK3 channel modulators. Synthesis and biological evaluation of 2-substituted tetrahydropyridine derivatives with potential anti-metastatic activity. Eur J Med Chem. 2020;186:111854.

Molecular Formula	C₂₅H₄₉NO
Molecular Weight	379.66