Thalidomide-NH-PEG2-COOH
Modify Date: 2024-01-13 11:13:13
Thalidomide-NH-PEG2-COOH structure
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Common Name | Thalidomide-NH-PEG2-COOH | ||
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| CAS Number | 2412056-45-0 | Molecular Weight | 433.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H23N3O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-NH-PEG2-COOHThalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
| Name | Thalidomide-NH-PEG2-COOH |
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| Description | Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C20H23N3O8 |
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| Molecular Weight | 433.41 |
| Hazard Codes | Xi |
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