Thalidomide-NH-PEG4-COOH

Modify Date: 2024-01-16 11:38:59

Thalidomide-NH-PEG4-COOH Structure
Thalidomide-NH-PEG4-COOH structure
Common Name Thalidomide-NH-PEG4-COOH
CAS Number 2412056-48-3 Molecular Weight 521.52
Density N/A Boiling Point N/A
Molecular Formula C24H31N3O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-NH-PEG4-COOH


Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].

 Names

Name Thalidomide-NH-PEG4-COOH

 Thalidomide-NH-PEG4-COOH Biological Activity

Description Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1].
Related Catalog
Target

Cereblon

In Vitro Thalidomide-NH-PEG4-COOH (S13) is the E3 ligase ligand-linker conjugate of dCBP-1 (HY-134582)[1].
References

[1]. Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.

 Chemical & Physical Properties

Molecular Formula C24H31N3O10
Molecular Weight 521.52
Storage condition -20°C
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