Steroid sulfatase-IN-3

Modify Date: 2024-01-13 09:20:42

Steroid sulfatase-IN-3 Structure
Steroid sulfatase-IN-3 structure
Common Name Steroid sulfatase-IN-3
CAS Number 2413880-53-0 Molecular Weight 384.88
Density N/A Boiling Point N/A
Molecular Formula C17H21ClN2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Steroid sulfatase-IN-3


Steroid sulfatase-IN-3 (compound 1q) is a potent STS (Steroid sulfatase) inhibitor, with an IC50 of 25.8 nM. Steroid sulfatase-IN-3 shows antiproliferative activity against T-47D estrogen-dependent breast cancer cells, with an IC50 of 1.04 µM[1].

 Names

Name Steroid sulfatase-IN-3

 Steroid sulfatase-IN-3 Biological Activity

Description Steroid sulfatase-IN-3 (compound 1q) is a potent STS (Steroid sulfatase) inhibitor, with an IC50 of 25.8 nM. Steroid sulfatase-IN-3 shows antiproliferative activity against T-47D estrogen-dependent breast cancer cells, with an IC50 of 1.04 µM[1].
Related Catalog
Target

IC50: 25.8 nM (STS, in JEG-3 cell lysate), 150.0 nM (STS, in JEG-3 cells)[1]

References

[1]. El-Gamal MI, et al. A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation. Bioorg Med Chem. 2020 Apr 15;28(8):115406.

 Chemical & Physical Properties

Molecular Formula C17H21ClN2O4S
Molecular Weight 384.88