COX-2-IN-14

Modify Date: 2024-01-11 16:16:55

COX-2-IN-14 structure	Common Name	COX-2-IN-14
	CAS Number	2428387-48-6	Molecular Weight	386.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₈N₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of COX-2-IN-14

COX-2-IN-14 (compound 2a) is a potent and selective COX-2 (cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site of COX-2 co-crystal. COX-2-IN-14 exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice[1].

Name	COX-2-IN-14

Description	COX-2-IN-14 (compound 2a) is a potent and selective COX-2 (cyclooxygenase-2) inhibitor. COX-2-IN-14 shows effective binding at the active site of COX-2 co-crystal. COX-2-IN-14 exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity in mice[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2
References	[1]. Gonçalves DS, et al. Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity. Bioorg Med Chem. 2020 Jun 15;28(12):115549.

Molecular Formula	C₁₈H₁₈N₄O₆
Molecular Weight	386.36

COX-2-IN-14

Use of COX-2-IN-14

Names

COX-2-IN-14 Biological Activity

Chemical & Physical Properties