![]() PROTAC STAT3 degrader-2 structure
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Common Name | PROTAC STAT3 degrader-2 | ||
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CAS Number | 2429877-78-9 | Molecular Weight | 1172.13 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C59H60F2N9O13P | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of PROTAC STAT3 degrader-2PROTAC STAT3 degrader-2 is a selective and efficacious PROTAC degrader of STAT3 protein with a DC50 of 3.54 μM in Molm-16 Cell. PROTAC STAT3 degrader-2 has the potential for cancer research[1]. |
Name | PROTAC STAT3 degrader-2 |
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Description | PROTAC STAT3 degrader-2 is a selective and efficacious PROTAC degrader of STAT3 protein with a DC50 of 3.54 μM in Molm-16 Cell. PROTAC STAT3 degrader-2 has the potential for cancer research[1]. |
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Related Catalog | |
Target |
STAT3:3.54 μM (ID50) |
In Vitro | PROTAC STAT3 degrader-2 (compound 27; 4 天) 在 Molm-16 具有细胞生长抑制活性,IC50 为 0.582 μM,对 SU-DHL-1 细胞作用低,IC50>10 μM[1]。 PROTAC STAT3 degrader-2 在高达 5 μM 无法降低 SU-DHL-1 细胞中的 STAT3 和 pSTATSY705 蛋白水平[1]。 |
References |
Molecular Formula | C59H60F2N9O13P |
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Molecular Weight | 1172.13 |