HIV-1 inhibitor-42

Modify Date: 2024-01-15 15:21:53

HIV-1 inhibitor-42 structure	Common Name	HIV-1 inhibitor-42
	CAS Number	2459929-46-3	Molecular Weight	424.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₀N₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HIV-1 inhibitor-42

HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 μM[1].

Name	HIV-1 inhibitor-42

Description	HIV-1 inhibitor-42 (compound 5b) is a potent HIV-1 inhibitor, with an IC50 of 0.06 μM. HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase and DNA-dependent DNA polymerase, with IC50 values of 0.518 and 0.072 μM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1:0.06 ± 0.0 μM (IC50) HIV-1 (Y181C):15.510 ± 1 μM (IC50) HIV-1 (K103N):53.045 ± 6 μM (IC50)
References	[1]. Yi-MingLi, et al. Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. September 2020;102:104041.

Molecular Formula	C₂₂H₂₀N₂O₅S
Molecular Weight	424.47

HIV-1 inhibitor-42

Use of HIV-1 inhibitor-42

Names

HIV-1 inhibitor-42 Biological Activity

Chemical & Physical Properties