DKFZ-748
Modify Date: 2024-09-16 10:12:50
DKFZ-748 structure
|
Common Name | DKFZ-748 | ||
|---|---|---|---|---|
| CAS Number | 2490709-68-5 | Molecular Weight | 329.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H23N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DKFZ-748DKFZ-748 is a selective HDAC10 inhibitor (pIC50=7.66), and shows anti-tumor activity[1]. |
| Name | DKFZ-748 |
|---|
| Description | DKFZ-748 is a selective HDAC10 inhibitor (pIC50=7.66), and shows anti-tumor activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | DKFZ-748 shows dose-dependent growth inhibition of HeLa cells in a polyamine-limiting in vitro tumor model[1]. DKFZ-748 (1-100 μM; 72 h) induces acetylation of BE(2)-C cells[1]. DKFZ 748 shows significant accumulation of N8 acetyl- and N1,8-diacetylspermidine in a dose-dependent manner[1]. Western Blot Analysis[1] Cell Line: BE(2)-C cells Concentration: 1, 10, 100 μM Incubation Time: 72 h Result: Induced significant acetylation only at the highest tested concentration (100 μM). |
| References |
| Molecular Formula | C18H23N3O3 |
|---|---|
| Molecular Weight | 329.39 |