CB2R probe 1

Modify Date: 2024-03-31 11:08:28

CB2R probe 1 Structure
CB2R probe 1 structure
Common Name CB2R probe 1
CAS Number 2634714-79-5 Molecular Weight 594.74
Density N/A Boiling Point N/A
Molecular Formula C36H42N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CB2R probe 1


CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells[1].

 Names

Name CB2R probe 1

 CB2R probe 1 Biological Activity

Description CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells[1].
Related Catalog
Target

cannabinoid type-2 receptors:130 nM (Ki)

In Vitro CB2R probe 1 (compound 28) (100 nM; 24 h) shows low cytotoxicity with IC50s of 1.6, 1.4, 1.4, 1.1, 2.6, 0.55, 2.0, 2.4, 2.8 nM for PANC1, U2OS, HT29, HT29-DX, U87AD, PC3, CB2R-HEK293, MCF7, MCFT-DX cells, respectively[1].
References

[1]. Spinelli F, et al. Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R). Eur J Med Chem. 2020 Feb 15;188:112037.

 Chemical & Physical Properties

Molecular Formula C36H42N4O4
Molecular Weight 594.74
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