Dehydrodiisoeugenol

Modify Date: 2024-01-04 16:42:04

Dehydrodiisoeugenol Structure
Dehydrodiisoeugenol structure
Common Name Dehydrodiisoeugenol
CAS Number 2680-81-1 Molecular Weight 326.386
Density 1.2±0.1 g/cm3 Boiling Point 452.0±45.0 °C at 760 mmHg
Molecular Formula C20H22O4 Melting Point N/A
MSDS N/A Flash Point 227.2±28.7 °C

 Use of Dehydrodiisoeugenol


Dehydrodiisoeugenol is isolated from Myristica fragrans Houtt, shows anti-inflammatory and anti-bacterial actions[1]. Dehydrodiisoeugenol inhibits LPS- stimulated NF-κB activation and cyclooxygenase (COX)-2 gene expression in murine macrophages[2].

 Names

Name 2-methoxy-4-[7-methoxy-3-methyl-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]phenol
Synonym More Synonyms

 Dehydrodiisoeugenol Biological Activity

Description Dehydrodiisoeugenol is isolated from Myristica fragrans Houtt, shows anti-inflammatory and anti-bacterial actions[1]. Dehydrodiisoeugenol inhibits LPS- stimulated NF-κB activation and cyclooxygenase (COX)-2 gene expression in murine macrophages[2].
Related Catalog
Target

NF-κB; COX-2[2]

References

[1]. Murakami Y, et al. Dehydrodiisoeugenol, an isoeugenol dimer, inhibits lipopolysaccharide-stimulated nuclear factor kappa B activation and cyclooxygenase-2 expression in macrophages. Arch Biochem Biophys. 2005 Feb 15;434(2):326-32.

[2]. Lv QQ, et al. Metabolic profiling of dehydrodiisoeugenol using xenobiotic metabolomics. J Pharm Biomed Anal. 2017 Oct 25;145:725-733.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 452.0±45.0 °C at 760 mmHg
Molecular Formula C20H22O4
Molecular Weight 326.386
Flash Point 227.2±28.7 °C
Exact Mass 326.151794
PSA 47.92000
LogP 4.19
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.596

 Synthetic Route

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Dehydrodiisoeugenol Structure

Dehydrodiisoeugenol

CAS#:2680-81-1

Literature: Drago, R. S.; Corden, B. B.; Barnes, C. W. Journal of the American Chemical Society, 1986 , vol. 108, # 9 p. 2453 - 2454

~22%

Dehydrodiisoeugenol Structure

Dehydrodiisoeugenol

CAS#:2680-81-1

Literature: Hernandez-Vazquez, Liliana; Olivera-Flores, Ma. Teresa De Jesus; Ruiz-Teran, Francisco; Ayala, Ivon; Navarro-Ocana, Arturo Journal of Molecular Catalysis B: Enzymatic, 2011 , vol. 72, # 3-4 p. 102 - 106

~26%

Dehydrodiisoeugenol Structure

Dehydrodiisoeugenol

CAS#:2680-81-1

Literature: Adilina, Indri Badria; Hara, Takayoshi; Ichikuni, Nobuyuki; Shimazu, Shogo Journal of Molecular Catalysis A: Chemical, 2012 , vol. 361-362, p. 72 - 79

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Dehydrodiisoeugenol Structure

Dehydrodiisoeugenol

CAS#:2680-81-1

Literature: Unno, Tatsuya; Kim, Soo-Jin; Kanaly, Robert A.; Ahn, Joong-Hoon; Kang, Su-Il; Hur, Hor-Gil Journal of Agricultural and Food Chemistry, 2007 , vol. 55, # 21 p. 8556 - 8561

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Dehydrodiisoeugenol Structure

Dehydrodiisoeugenol

CAS#:2680-81-1

Literature: Cousin; Herissey Bulletin de la Societe Chimique de France, 1908 , vol. <4> 3, p. 1070,1073 Full Text Show Details Cousin; Herissey Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1908 , vol. 147, p. 247 Bulletin de la Societe Chimique de France, 1908 , vol. <4> 3, p. 1070 Chem. Zentralbl., 1908 , vol. 79, # II p. 1101

~%

Dehydrodiisoeugenol Structure

Dehydrodiisoeugenol

CAS#:2680-81-1

Literature: Cousin; Herissey Bulletin de la Societe Chimique de France, 1908 , vol. <4> 3, p. 1070,1073 Full Text Show Details Cousin; Herissey Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1908 , vol. 147, p. 247 Bulletin de la Societe Chimique de France, 1908 , vol. <4> 3, p. 1070 Chem. Zentralbl., 1908 , vol. 79, # II p. 1101

~%

Dehydrodiisoeugenol Structure

Dehydrodiisoeugenol

CAS#:2680-81-1

Literature: Erdtman Biochemische Zeitschrift, 1933 , vol. 258, p. 172,179 Justus Liebigs Annalen der Chemie, 1933 , vol. 503, p. 283,286

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Detail
Literature: Lindberg Svensk Papperstidning, 1953 , vol. 56, p. 6

 Synonyms

Isoeugenol,dehydrodi
DEHRODIISOEUGENOL
Phenol, 4-[2,3-dihydro-7-methoxy-3-methyl-5-[(1E)-1-propen-1-yl]-2-benzofuranyl]-2-methoxy-
Diisoeugenol,dehydro
dehydrodiisoeugenol
2-Methoxy-4-{7-methoxy-3-methyl-5-[(1E)-1-propen-1-yl]-2,3-dihydro-1-benzofuran-2-yl}phenol
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