Metolazone-d7

Modify Date: 2024-01-05 22:39:14

Metolazone-d7 Structure
Metolazone-d7 structure
Common Name Metolazone-d7
CAS Number 2714484-71-4 Molecular Weight 372.88
Density N/A Boiling Point N/A
Molecular Formula C16H9D7ClN3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Metolazone-d7


Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.

 Names

Name Metolazone-d7

 Metolazone-d7 Biological Activity

Description Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Stern A. Metolazone, a diuretic agent. Am Heart J. 1976 Feb;91(2):262-3.

[3]. Thompson DM. A new antihypertensive: metolazone treatment of hypertension. J Kans Med Soc. 1977 Jul;78(7):337-9, 342.

 Chemical & Physical Properties

Molecular Formula C16H9D7ClN3O3S
Molecular Weight 372.88