2714484-71-4

2714484-71-4 structure
2714484-71-4 structure
  • Name: Metolazone-d7
  • Chemical Name: Metolazone-d7
  • CAS Number: 2714484-71-4
  • Molecular Formula: C16H9D7ClN3O3S
  • Molecular Weight: 372.88
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Thrombin
  • Create Date: 2022-07-01 21:47:18
  • Modify Date: 2024-01-05 22:39:14
  • Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.

Name Metolazone-d7
Description Metolazone-d7 is deuterium labeled Metolazone. Metolazone (SR-720-22) is primarily used to treat congestive heart failure and high blood pressure.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Stern A. Metolazone, a diuretic agent. Am Heart J. 1976 Feb;91(2):262-3.

[3]. Thompson DM. A new antihypertensive: metolazone treatment of hypertension. J Kans Med Soc. 1977 Jul;78(7):337-9, 342.

Molecular Formula C16H9D7ClN3O3S
Molecular Weight 372.88