PF-6870961
Modify Date: 2024-04-09 15:39:12
PF-6870961 structure
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Common Name | PF-6870961 | ||
|---|---|---|---|---|
| CAS Number | 2857112-06-0 | Molecular Weight | 528.67 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H32N6O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-6870961PF-6870961 is an inverse agonist of GHSR1a with Ki values of 73.6 nM (human GHSR), 239 nM (rat GHSR), and 217 nM (dog GHSR), respectively. PF-6870961 inhibits the constitutive GHSR1a-induced IP accumulation with an IC50 value of 300 nM. PF-6870961 also inhibits constitutive GHSR1a β-arrestin mobilization with an IC50 value of 1.10 nM[1]. |
| Name | PF-6870961 |
|---|
| Description | PF-6870961 is an inverse agonist of GHSR1a with Ki values of 73.6 nM (human GHSR), 239 nM (rat GHSR), and 217 nM (dog GHSR), respectively. PF-6870961 inhibits the constitutive GHSR1a-induced IP accumulation with an IC50 value of 300 nM. PF-6870961 also inhibits constitutive GHSR1a β-arrestin mobilization with an IC50 value of 1.10 nM[1]. |
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| Related Catalog | |
| In Vivo | PF-6870961 (40 mg/kg; i.p.) suppresses food intake in both satiated and fasted rats[1]. Animal Model: Satiated and fasted rats model[1] Dosage: 2.5 mg/kg, 10 mg/kg, and 40 mg/kg Administration: Intraperitoneal injection Result: Significantly reduced food intake at 40 mg/kg. |
| References |
| Molecular Formula | C29H32N6O2S |
|---|---|
| Molecular Weight | 528.67 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: PF-6870961
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: PF-6870961
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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