Br-PEG6-CH2COOtBu

Modify Date: 2024-01-09 20:06:25

Br-PEG6-CH2COOtBu Structure
Br-PEG6-CH2COOtBu structure
Common Name Br-PEG6-CH2COOtBu
CAS Number 297162-48-2 Molecular Weight 459.37
Density N/A Boiling Point N/A
Molecular Formula C18H35BrO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Br-PEG6-CH2COOtBu


Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Br-PEG6-CH2COOtBu

 Br-PEG6-CH2COOtBu Biological Activity

Description Br-PEG6-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C18H35BrO8
Molecular Weight 459.37