S26948

Modify Date: 2024-01-27 18:29:55

S26948 structure	Common Name	S26948
	CAS Number	353280-43-0	Molecular Weight	519.56600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₅NO₇S	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of S26948

S26948 is a specific peroxisome proliferator-activated receptor γ (PPARγ) modulator (EC50=8.83 nM) with potent antidiabetes and antiatherogenic effects. S26948 is a specific high-affinity agonist for PPARγ[1].

Name	dimethyl 2-[[4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3-yl)ethoxy]phenyl]methyl]propanedioate
Synonym	More Synonyms

Description	S26948 is a specific peroxisome proliferator-activated receptor γ (PPARγ) modulator (EC50=8.83 nM) with potent antidiabetes and antiatherogenic effects. S26948 is a specific high-affinity agonist for PPARγ[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
References	[1]. Maria Carmen Carmona, et al. S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects. Diabetes. 2007 Nov;56(11):2797-808.

Molecular Formula	C₂₈H₂₅NO₇S
Molecular Weight	519.56600
Exact Mass	519.13500
PSA	129.14000
LogP	3.87770

S26948 MSDS(Chinese)

RIDADR	NONH for all modes of transport

N/A

CAS#:353280-40-7

~83%

S26948

CAS#:353280-43-0

Literature: Blanc-Delmas, Elodie; Lebegue, Nicolas; Wallez, Valerie; Leclerc, Veronique; Yous, Said; Carato, Pascal; Farce, Amaury; Bennejean, Caroline; Renard, Pierre; Caignard, Daniel-Henri; Audinot-Bouchez, Valerie; Chomarat, Pascale; Boutin, Jean; Hennuyer, Nathalie; Louche, Katie; Carmona, Maria Carmen; Staels, Bart; Penicaud, Luc; Casteilla, Louis; Lonchampt, Michel; Dacquet, Catherine; Chavatte, Philippe; Berthelot, Pascal; Lesieur, Daniel Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 22 p. 7377 - 7391