5-(6-dimethylaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol

Modify Date: 2024-01-29 18:21:42

5-(6-dimethylaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol Structure
5-(6-dimethylaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol structure
Common Name 5-(6-dimethylaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
CAS Number 35665-58-8 Molecular Weight 279.30
Density 1.59g/cm3 Boiling Point 565.4ºC at 760 mmHg
Molecular Formula C12H17N5O3 Melting Point N/A
MSDS N/A Flash Point 295.8ºC

 Use of 5-(6-dimethylaminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol


N6-Dimethyldeoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-[6-(dimethylamino)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol
Synonym More Synonyms

  Biological Activity

Description N6-Dimethyldeoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.59g/cm3
Boiling Point 565.4ºC at 760 mmHg
Molecular Formula C12H17N5O3
Molecular Weight 279.30
Flash Point 295.8ºC
Exact Mass 279.13300
PSA 96.53000
Index of Refraction 1.73

 Synthetic Route

 Synonyms

N6,N6-dimethyl-2'-deoxyadenosine
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