Antituberculosis agent-3

Modify Date: 2024-04-03 13:55:11

Antituberculosis agent-3 structure	Common Name	Antituberculosis agent-3
	CAS Number	369606-71-3	Molecular Weight	490.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₀BrN₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antituberculosis agent-3

Antituberculosis agent-3 (Compound 2) is an antituberculosis agent. Antituberculosis agent-3 shows anti-mycobacterial activity, and can inhibit M. tuberculosis H37Rv strain growth (MIC=12.5 μg/mL)[1].

Name	Antituberculosis agent-3

Description	Antituberculosis agent-3 (Compound 2) is an antituberculosis agent. Antituberculosis agent-3 shows anti-mycobacterial activity, and can inhibit M. tuberculosis H37Rv strain growth (MIC=12.5 μg/mL)[1].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antituberculosis agent-3 (0-100 μM; 60 min) shows no inhibition of PknB activity[1]. Cell Viability Assay[1] Cell Line: M. tuberculosis Concentration: 0-100 μM Incubation Time: 60 min Result: Displayed no PknB inhibition (IC50>128 μM).
References	[1]. Paptawan Thongdee, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.

Molecular Formula	C₂₁H₂₀BrN₃O₄S
Molecular Weight	490.37