Antituberculosis agent-7

Modify Date: 2024-01-07 17:44:41

Antituberculosis agent-7 Structure
Antituberculosis agent-7 structure
Common Name Antituberculosis agent-7
CAS Number 2874263-73-5 Molecular Weight 469.43
Density N/A Boiling Point N/A
Molecular Formula C26H19F4NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antituberculosis agent-7


Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv[1].

 Names

Name Antituberculosis agent-7

 Antituberculosis agent-7 Biological Activity

Description Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv[1].
Related Catalog
In Vitro Antituberculosis agent-7 (compound 9h) 对 E. coli,B. subtilis,S. albus,C. albicans 的 MIC 分别为 >250 μM、250 μM、>250 μM、250 μM[1]。
References

[1]. Abhijit Shinde, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107.  

 Chemical & Physical Properties

Molecular Formula C26H19F4NO3
Molecular Weight 469.43