2874263-73-5

2874263-73-5 structure

Name: Antituberculosis agent-7
Chemical Name: Antituberculosis agent-7
CAS Number: 2874263-73-5
Molecular Formula: C₂₆H₁₉F₄NO₃
Molecular Weight: 469.43
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-03-11 08:19:41
Modify Date: 2024-01-07 17:44:41
Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv[1].

Name	Antituberculosis agent-7

Description	Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Antituberculosis agent-7 (compound 9h) 对 E. coli，B. subtilis，S. albus，C. albicans 的 MIC 分别为 >250 μM、250 μM、>250 μM、250 μM[1]。
References	[1]. Abhijit Shinde, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107.

Molecular Formula	C₂₆H₁₉F₄NO₃
Molecular Weight	469.43