YE 120

Modify Date: 2024-01-08 21:41:22

YE 120 structure	Common Name	YE 120
	CAS Number	383124-82-1	Molecular Weight	330.16800
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₉Cl₂N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of YE 120

YE120 is a potent GPR35 agonist with an EC50 of 32.5 nM[1].

Name	[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]m alononitrile
Synonym	More Synonyms

Description	YE120 is a potent GPR35 agonist with an EC50 of 32.5 nM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Deng H, et al. Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J Med Chem. 2011 Oct 27;54(20):7385-96.

Molecular Formula	C₁₆H₉Cl₂N₃O
Molecular Weight	330.16800
Exact Mass	329.01200
PSA	80.60000
LogP	4.38014

3-hydroxy-3-[3'...

CAS#:436097-03-9

Malononitrile

CAS#:109-77-3

~26%

YE 120

CAS#:383124-82-1

Literature: Deng, Huayun; Fang, Ye; He, Mingqian; Hu, Haibei; Niu, Weijun; Sun, Haiyan Patent: US2012/22116 A1, 2012 ; Location in patent: Page/Page column 53 ;