Shanghai Nianxing Industrial Co., Ltd
China
Product Name: YE 120
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

ShangHai DC Chemicals Co.,Ltd
China
Product Name: YE-120
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

DC Chemicals Limited
China
Product Name: YE-120
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

383124-82-1

383124-82-1 structure

383124-82-1 structure

Name: YE 120
Chemical Name: [3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]m alononitrile
CAS Number: 383124-82-1
Molecular Formula: C₁₆H₉Cl₂N₃O
Molecular Weight: 330.16800
Create Date: 2016-06-08 08:10:17
Modify Date: 2024-01-08 21:41:22
YE120 is a potent GPR35 agonist with an EC50 of 32.5 nM[1].

Name	[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]m alononitrile
Synonyms	2-Dicyanmethylen-3-cyan-4,6-dimethyl-1,2-dihydro-pyridin 1,2-Dihydro-2-dicyanmethylen-3-cyan-4,6-dimethylpyridin 3-cyano-2-dicyanomethylene-4,6-dimethyl-1,2-dihydropyridine Fatostatin A

Description	YE120 is a potent GPR35 agonist with an EC50 of 32.5 nM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Deng H, et al. Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J Med Chem. 2011 Oct 27;54(20):7385-96.

Molecular Formula	C₁₆H₉Cl₂N₃O
Molecular Weight	330.16800
Exact Mass	329.01200
PSA	80.60000
LogP	4.38014

436097-03-9 structure

436097-03-9

109-77-3 structure

109-77-3

~26%

383124-82-1 structure

383124-82-1

Literature: Deng, Huayun; Fang, Ye; He, Mingqian; Hu, Haibei; Niu, Weijun; Sun, Haiyan Patent: US2012/22116 A1, 2012 ; Location in patent: Page/Page column 53 ;

Precursor 2
436097-03-9 109-77-3
DownStream 0