1,N6-Ethenoadenosine

Modify Date: 2024-01-05 07:15:10

1,N6-Ethenoadenosine Structure
1,N6-Ethenoadenosine structure
Common Name 1,N6-Ethenoadenosine
CAS Number 39007-51-7 Molecular Weight 291.26
Density 1.99g/cm3 Boiling Point N/A
Molecular Formula C12H13N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1,N6-Ethenoadenosine


1,N6-Ethenoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1 n6-ethenoadenosine free base
Synonym More Synonyms

 1,N6-Ethenoadenosine Biological Activity

Description 1,N6-Ethenoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.99g/cm3
Molecular Formula C12H13N5O4
Molecular Weight 291.26
Exact Mass 291.09700
PSA 117.93000
Index of Refraction 1.915

 Synthetic Route

~15%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Guengerich, F. Peter; Raney, Veronica M. Journal of the American Chemical Society, 1992 , vol. 114, # 3 p. 1074 - 1080

~10%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Nair, Vasu; Offerman, Rick J.; Turner, Gregory A. Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4021 - 4025

~%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Inoue, Yasuo; Kuramochi, Takao; Sakurai, Michiharu; Tazawa, Ichiro Journal of the American Chemical Society, 1980 , vol. 102, # 17 p. 5574 - 5577

~%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Inoue, Yasuo; Kuramochi, Takao; Sakurai, Michiharu; Tazawa, Ichiro Journal of the American Chemical Society, 1980 , vol. 102, # 17 p. 5574 - 5577

~5%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Kronberg, Leif; Asplund, Deanne; Maeki, Jukka; Sjoeholm, Rainer Chemical Research in Toxicology, 1996 , vol. 9, # 8 p. 1257 - 1263

~70%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Patching, Simon G.; Baldwin, Stephen A.; Baldwin, Alexander D.; Young, James D.; Gallagher, Maurice P.; Henderson, Peter J. F.; Herbert, Richard B. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 3 p. 462 - 470

~%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Mikkola, Satu; Koissi, Niangoran; Ketomaeki, Kaisa; Rauvala, Susanna; Neuvonen, Kari; Loennberg, Harri European Journal of Organic Chemistry, 2000 , # 12 p. 2315 - 2323

~%

1,N6-Ethenoadenosine Structure

1,N6-Ethenoadenosine

CAS#:39007-51-7

Literature: Mikkola, Satu; Koissi, Niangoran; Ketomaeki, Kaisa; Rauvala, Susanna; Neuvonen, Kari; Loennberg, Harri European Journal of Organic Chemistry, 2000 , # 12 p. 2315 - 2323

 Synonyms

Ethenoadenosine
N6-Ethenoadenosine
1,N6-ethanoadenosine
1,N6-etheno-adenosine