2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Modify Date: 2024-02-03 21:13:38

2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol structure	Common Name	2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
	CAS Number	3969-27-5	Molecular Weight	297.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₅N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

8-Methoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Name	Adenosine, 8-methoxy
Synonym	More Synonyms

Description	8-Methoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Molecular Formula	C₁₁H₁₅N₅O₅
Molecular Weight	297.27
Exact Mass	297.10700
PSA	148.77000

Sodium Methylate

CAS#:124-41-4

8-Bromoadenosine

CAS#:2946-39-6

~79%

2-(6-amino-8-me...

CAS#:3969-27-5

Literature: Buenger; Nair Synthesis, 1990 , vol. 1, # 10 p. 962 - 966

Methanol

CAS#:67-56-1

2',3',5'-TRI-O-...

CAS#:23205-66-5

2-(6-amino-8-me...

CAS#:3969-27-5

Literature: Liu, Jie; Barrio, Jorge R.; Satyamurthy, Nagichettiar Journal of Fluorine Chemistry, 2006 , vol. 127, # 9 p. 1175 - 1187

Methanol

CAS#:67-56-1

2',3',5'-TRI-O-...

CAS#:23205-66-5

2-(6-amino-8-me...

CAS#:3969-27-5

8-Aminoadenosine

CAS#:3868-33-5

Literature: Liu, Jie; Barrio, Jorge R.; Satyamurthy, Nagichettiar Journal of Fluorine Chemistry, 2006 , vol. 127, # 9 p. 1175 - 1187

Precursor 4
CAS#:124-41-4 Sodium Methylate CAS#:2946-39-6 8-Bromoadenosine CAS#:67-56-1 Methanol CAS#:23205-66-5 2',3',5'-TRI-O-...
DownStream 0

8-methoxyacenaphthen-1-one

8-Methoxyadenosine

8-Methoxy-acenaphthen-1-on

8-Methoxyadenosin

2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Use of 2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms