ST-148
Modify Date: 2024-01-19 18:22:06
ST-148 structure
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Common Name | ST-148 | ||
|---|---|---|---|---|
| CAS Number | 400863-77-6 | Molecular Weight | 421.537 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H19N5OS2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ST-148ST-148 a novel potent, broad-spetrum inhibitor of dengue virus (DENV) replication, inhibits DENV-2 wth EC50 of 16 nM in viral titer reduction assays, interacts with the DENV Capsid protein; exhibits a broad range of potencies with EC50 of 0.512, 1.150, and 2.832 uM for DENV-3, -4, and -1, respectively; significantly reduced viremia and viral load in vital organs and tended to lower cytokine levels in the plasma in a nonlethal model of DENV infection in AG129 mice. |
| Name | ST-148 |
|---|
| Description | ST-148 a novel potent, broad-spetrum inhibitor of dengue virus (DENV) replication, inhibits DENV-2 wth EC50 of 16 nM in viral titer reduction assays, interacts with the DENV Capsid protein; exhibits a broad range of potencies with EC50 of 0.512, 1.150, and 2.832 uM for DENV-3, -4, and -1, respectively; significantly reduced viremia and viral load in vital organs and tended to lower cytokine levels in the plasma in a nonlethal model of DENV infection in AG129 mice. |
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| References | References 1. Byrd CM, et al. Antimicrob Agents Chemother. 2013 Jan;57(1):15-25. 2. Scaturro P, et al. J Virol. 2014 Oct;88(19):11540-55. View Related Products by Target Filovirus |
| Molecular Formula | C21H19N5OS2 |
|---|---|
| Molecular Weight | 421.537 |