ST 045849

Modify Date: 2024-01-08 17:33:28

ST 045849 Structure
ST 045849 structure
Common Name ST 045849
CAS Number 442665-87-4 Molecular Weight 446.99
Density N/A Boiling Point N/A
Molecular Formula C23H27ClN2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ST 045849


OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.

 Names

Name OGT-IN-2

 ST 045849 Biological Activity

Description OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C23H27ClN2O3S
Molecular Weight 446.99

 Safety Information

Hazard Codes Xi