Name | OGT-IN-2 |
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Description | OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice. |
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Related Catalog |
Molecular Formula | C23H27ClN2O3S |
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Molecular Weight | 446.99 |
Hazard Codes | Xi |
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