5'-O-Dimethoxytrityl-deoxythymidine structure
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Common Name | 5'-O-Dimethoxytrityl-deoxythymidine | ||
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CAS Number | 40615-39-2 | Molecular Weight | 528.596 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
Molecular Formula | C31H32N2O7 | Melting Point | 114-116 °C (subl.)(lit.) | |
MSDS | Chinese USA | Flash Point | N/A |
Use of 5'-O-Dimethoxytrityl-deoxythymidine5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides[1]. |
Name | 5'-O-(4,4'-Dimethoxytrityl)thymidine |
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Synonym | More Synonyms |
Description | 5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative which can be used in the preparation of oligonucleotides[1]. |
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Related Catalog | |
References |
[1]. Lars Holmberg. Method and means for oligonucleotide synthesis. WO1992009615A1. |
Density | 1.2±0.1 g/cm3 |
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Melting Point | 114-116 °C (subl.)(lit.) |
Molecular Formula | C31H32N2O7 |
Molecular Weight | 528.596 |
Exact Mass | 528.226013 |
PSA | 112.01000 |
LogP | 6.97 |
Index of Refraction | 1.596 |
Storage condition | −20°C |
Stability | Store in Freezer |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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Hazard Codes | Xi:Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 29349990 |
Precursor 10 | |
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DownStream 10 | |
HS Code | 29349990 |
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Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method.
Nucleic Acids Res. 8(22) , 5473-89, (1980) Synthesis of two oligothymidylic acids, tridecamer and nonadecamer, is described by a rapid and simple solid-phase method on two kinds of polyacrylamide supports derivatized from commercially availabl... |
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Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.
Nucleic Acids Res. 10(10) , 3291-301, (1982) A method for the synthesis of mixed dimers, trimers and oligonucleotides on a solid support using monomeric protected nucleoside phosphochloridites (1a-d) has been developed and the different nucleosi... |
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Synthesis of 14 C-radiolabeled oligonucleotides with a novel phosphoramidite reagent.
Bioorg. Med. Chem. Lett. 8(9) , 1123-6, (1998) A novel solid-phase synthesis of 5'-radiolabeled oligonucleotides is described. The labeling reaction is carried out by the phosphoramidite method with the aid of [4,6-di-14C]-5'-dimethoxytritylthymid... |
Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- |
5'-O-dimethyltritylthymidine |
5'-O-(Bis(4-methoxyphenyl)phenylmethyl)thymidine |
EINECS 255-003-1 |
2,4(1H,3H)-pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-glycero-pentofuranosyl]-5-methyl- |
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-[(2R,5S)-tetrahydro-5-[1-methoxy-1-(methyldioxy)-2,2,2-triphenylethyl]-2-furanyl]- |
1-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-β-D-glycero-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione |
MFCD00010113 |
5′-O-(4,4′-Dimethoxytrityl)thymidine |
5'-O-Dimethoxytrityl-deoxythymidine |
1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione |
DMTr-dThd |
5‘-O-Dimethoxytrityl-deoxythymidine |
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]thymidine |
1-{(2R,5S)-5-[1-Methoxy-1-(methylperoxy)-2,2,2-triphenylethyl]tetrahydro-2-furanyl}-5-methyl-2,4(1H,3H)-pyrimidinedione |