Aromadendrin structure
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Common Name | Aromadendrin | ||
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CAS Number | 480-20-6 | Molecular Weight | 288.252 | |
Density | 1.6±0.1 g/cm3 | Boiling Point | 639.0±55.0 °C at 760 mmHg | |
Molecular Formula | C15H12O6 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 247.3±25.0 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of AromadendrinDihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic drugs[1]. |
Name | (+)-dihydrokaempferol |
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Synonym | More Synonyms |
Description | Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic drugs[1]. |
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Related Catalog | |
Target |
Apoptosis; Bcl-2; Bcl-xL[1] |
In Vitro | Dihydrokaempferol (0.3-300 μM; 48 hours) has no significant effect on normal synoviocytes, but dependently decreases the viability of RA-FLSs[1]. Dihydrokaempferol (3-30 μM; 48 hours) increases the percentage of apoptotic cells (including early and late apoptotic cells; ~3.8% and ~9.6%, respectively)[1]. Dihydrokaempferol (3-30 μM; 48 hours) promotes Bax and Bad expression and inhibits Bcl-2 and Bcl-xL expression, increases the cleaved fragments of caspase-3, caspase-9 and cleaved PARP[1]. Cell Proliferation Assay[1] Cell Line: Normal synoviocyte cells; RA-FLS cells Concentration: 0.3 μM, 3 μM, 30 μM, 300 μM Incubation Time: 48 hours Result: Decreased the proliferation of RA-FLSs. Apoptosis Analysis[1] Cell Line: RA-FLS cells Concentration: 3 μM, 30 μM Incubation Time: 48 hours Result: Induced apoptosis in RA-FLSs. Western Blot Analysis[1] Cell Line: RA-FLS cells Concentration: 3 μM, 30 μM Incubation Time: 48 hours Result: Promoted Bax and Bad expression, increased the cleaved fragments of caspase-3, caspase-9 and cleaved PARP and inhibited Bcl-2 and Bcl-xL expression. |
References |
Density | 1.6±0.1 g/cm3 |
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Boiling Point | 639.0±55.0 °C at 760 mmHg |
Molecular Formula | C15H12O6 |
Molecular Weight | 288.252 |
Flash Point | 247.3±25.0 °C |
Exact Mass | 288.063385 |
PSA | 107.22000 |
LogP | 2.42 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.729 |
Storage condition | ?20°C |
~% Aromadendrin CAS#:480-20-6 |
Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
~% Aromadendrin CAS#:480-20-6 |
Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
~% Aromadendrin CAS#:480-20-6 |
Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
~% Aromadendrin CAS#:480-20-6 |
Literature: Takahashi, Hiroshi; Kubota, Yumiko; Igushi, Mieko; Fang, Lin; Onda, Masayuki Heterocycles, 1986 , vol. 24, # 2 p. 369 - 377 |
Transcriptome sequencing and metabolite analysis reveals the role of delphinidin metabolism in flower colour in grape hyacinth.
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Functional characterization of a Plagiochasma appendiculatum flavone synthase I showing flavanone 2-hydroxylase activity.
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Production of 7-O-methyl aromadendrin, a medicinally valuable flavonoid, in Escherichia coli.
Appl. Environ. Microbiol. 78(3) , 684-94, (2012) 7-O-Methyl aromadendrin (7-OMA) is an aglycone moiety of one of the important flavonoid-glycosides found in several plants, such as Populus alba and Eucalyptus maculata, with various medicinal applica... |
4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, (2R-trans)- |
Katuranin |
(2R,3R)-3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one |
(+)-dihydrokaempferol |
Aromadedrin |
Aromadendrin |
4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-, (2R,3R)- |
DIHYDROKAEMPFEROL |