Gentisein

Modify Date: 2024-01-04 19:49:29

Gentisein structure	Common Name	Gentisein
	CAS Number	529-49-7	Molecular Weight	244.20000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₈O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Gentisein

Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM[1][2].

Name	gentisein
Synonym	More Synonyms

Description	Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798. [2]. Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2.

Description

Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 µM[1][2].

Related Catalog

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

References

[1]. Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798.

[2]. Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2.

Molecular Formula	C₁₃H₈O₅
Molecular Weight	244.20000
Exact Mass	244.03700
PSA	90.90000
LogP	2.06300

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6122400

CHEMICAL NAME :: Xanthen-9-one, 1,3,7-trihydroxy-

CAS REGISTRY NUMBER :: 529-49-7

BEILSTEIN REFERENCE NO. :: 0384687

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H8-O5

MOLECULAR WEIGHT :: 244.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985

HS Code	2932999099

Precursor 8
CAS#:108-73-6 Phloroglucinol CAS#:490-79-9 Gentisic acid CAS#:39838-86-3 7-hydroxy-1,3-d... CAS#:2150-46-1 Methyl2,5-dihyd...
CAS#:106296-25-7 methyl 2,5-bis(... CAS#:3722-54-1 9H-Xanthen-9-on... CAS#:491-64-5 1,3-Dihydroxy-7... CAS#:42833-59-0 2'-Hydroxy-2,4'...
DownStream 6
CAS#:529-61-3 Euxanthone CAS#:136083-95-9 (8-acetyloxy-6-... CAS#:13379-35-6 1-HYDROXY-3,7-D... CAS#:3722-54-1 9H-Xanthen-9-on...
CAS#:842-51-3 2,6-dimethoxyxa... CAS#:437-50-3 Gentisin

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Gentisein

9H-Xanthen-9-one,1,3,7-trihydroxy

1,3,7-trihydroxy-9H-xanthen-9-one

1,3,7-trihydroxy-xanthen-9-one

Xanthen-9-one,1,3,7-trihydroxy

1,3,7-Trihydroxy-xanthen-9-on

XANTHONE DERIV

1,3,7-trihydroxyxanthone

1,3,7-trihydroxyxanthen-9-one

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Gentisein
Price: Click To Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

BioBioPha
China
Product Name: Gentisein
Price: ￥3400.0/5mg
Purity: 96.0%
Delivery: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Gentisein
Price: ￥2748.0/5mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Gentisein
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 9H-Xanthen-9-one,1,3,7-trihydroxy-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: gentisein
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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