4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

Modify Date: 2024-01-06 08:52:11

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Structure
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID structure
Common Name 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
CAS Number 53005-05-3 Molecular Weight 454.52000
Density 1.54g/cm3 Boiling Point N/A
Molecular Formula C16H10N2O6S4 Melting Point >400ºC
MSDS N/A Flash Point N/A

 Use of 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID


DIDS is a potent RAD51 inhibitor. DIDS inhibits the RAD51-mediated homologous pairing and strand-exchange reactions. DIDS inhibits anion exchange and binding to the red blood cell membrane[1][2].

 Names

Name 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid
Synonym More Synonyms

  Biological Activity

Description DIDS is a potent RAD51 inhibitor. DIDS inhibits the RAD51-mediated homologous pairing and strand-exchange reactions. DIDS inhibits anion exchange and binding to the red blood cell membrane[1][2].
Related Catalog
In Vitro DIDS (0-10 μM) 抑制 RAD51 介导的链交换[1]。 DIDS (0-20 μM) 通过 RAD51 抑制 DNA 结合[1]。 DIDS (10 μM; 0-60 分钟) 在 DNA 不存在的情况下刺激 RAD51 的 ATP 水解活性[1]。
References

[1]. Ishida T, et, al. DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange. Nucleic Acids Res. 2009 Jun;37(10):3367-76.  

[2]. Lepke S, et, al. A study of the relationship between inhibition of anion exchange and binding to the red blood cell membrane of 4,4'-diisothiocyano stilbene-2,2'-disulfonic acid (DIDS) and its dihydro derivative (H2DIDS). J Membr Biol. 1976 Oct 20;29(1-2):147-77.  

 Chemical & Physical Properties

Density 1.54g/cm3
Melting Point >400ºC
Molecular Formula C16H10N2O6S4
Molecular Weight 454.52000
Exact Mass 453.94200
PSA 214.40000
LogP 5.98060
Index of Refraction 1.693

 Safety Information

HS Code 2930909090

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

dids
4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid
4,4'-diisothiocyanato-stilbene-2,2'-disulfonic acid
trans-4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid
4,4'-diisothiocyanato-2,2'-stilbenedisulfoneic acid
4,4'-diisothiocyanostilbene-2-2'-disulphonic acid
5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid
4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid
Top Suppliers:I want be here


Get all suppliers and price by the below link:

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID suppliers

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID price