Protoporphyrin IX

Modify Date: 2024-01-02 11:22:38

Protoporphyrin IX Structure
Protoporphyrin IX structure
Common Name Protoporphyrin IX
CAS Number 553-12-8 Molecular Weight 562.658
Density 1.3±0.1 g/cm3 Boiling Point 1122.0±65.0 °C at 760 mmHg
Molecular Formula C34H34N4O4 Melting Point N/A
MSDS Chinese USA Flash Point 632.4±34.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Protoporphyrin IX


Protoporphyrin IX is the final intermediate in the heme biosynthetic pathway.

 Names

Name protoporphyrin
Synonym More Synonyms

 Protoporphyrin IX Biological Activity

Description Protoporphyrin IX is the final intermediate in the heme biosynthetic pathway.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Yasushi Nakai, et al.Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1122.0±65.0 °C at 760 mmHg
Molecular Formula C34H34N4O4
Molecular Weight 562.658
Flash Point 632.4±34.3 °C
Exact Mass 562.257996
PSA 130.90000
LogP 7.33
Appearance of Characters Powder | purple
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.674
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P280-P305 + P351 + P338-P337 + P313
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26;S36
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles92

More Articles
Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells.

Br. J. Cancer 111(5) , 874-82, (2014)

Standard therapy for acute promyelocytic leukaemia (APL) includes retinoic acid (all-trans retinoic acid (ATRA)), which promotes differentiation of promyelocytic blasts. Although co-administration of ...

Indomethacin inhibits activation of endothelial nitric oxide synthase in the rat kidney: possible role of this effect in the pathogenesis of indomethacin-induced renal damage.

Chem. Biol. Interact. 221 , 77-87, (2014)

The clinical use of non-steroidal anti-inflammatory drugs (NSAIDs) is often associated with adverse effects in the kidney. Indomethacin, an NSAID that has been shown to induce oxidative stress in the ...

Comparison of protoporphyrin IX produced cell proliferation inhibition between human breast cancer MCF-7 and MDA-MB-231 cells.

Pharmazie 69(8) , 621-8, (2014)

Protoporphyrin IX (PpIX) is an effective hematoporphyrin derivative, widely adopted in photodynamic therapy (PDT) and sonodynamic therapy (SDT). As a sensitizer, PpIX could significantly enhance laser...

 Synonyms

3,3'-(3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphyrindiyl)dipropanoic acid
3,3'-(7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-diyl)dipropanoic acid
Kammerer's prophyrin
1,3,5,8-Tetramethyl-2,4-divinylporphine-6,7-dipropionic Acid
MFCD00151109
3,3'-(3,7,12,17-Tetramethyl-8,13-divinylporphyrin-2,18-diyl)dipropanoic acid
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-
protoporphyrin
EINECS 209-033-7
Kammerer's porphyrin
protoporphyrin-IX
7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid
Protoporphyrin IX
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