Nimustine HCL
Modify Date: 2024-01-02 17:01:05
Nimustine HCL structure
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Common Name | Nimustine HCL | ||
|---|---|---|---|---|
| CAS Number | 55661-38-6 | Molecular Weight | 309.152 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H14Cl2N6O2 | Melting Point | 186 °C | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of Nimustine HCLNimustine hydrochloride (ACNU) is a DNA cross-linking and DNA alkylating agent, which induces DNA replication blocking lesions and DNA double-strand breaks and inhibits DNA synthesis, commonly used in chemotherapy for glioblastomas[1][2][3]. |
| Name | nimustine hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Nimustine hydrochloride (ACNU) is a DNA cross-linking and DNA alkylating agent, which induces DNA replication blocking lesions and DNA double-strand breaks and inhibits DNA synthesis, commonly used in chemotherapy for glioblastomas[1][2][3]. |
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| Related Catalog | |
| References |
| Melting Point | 186 °C |
|---|---|
| Molecular Formula | C9H14Cl2N6O2 |
| Molecular Weight | 309.152 |
| Exact Mass | 308.055542 |
| PSA | 113.57000 |
| LogP | 2.57310 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Phrases | R25:Toxic if swallowed. |
| Safety Phrases | S36/37/39-S45 |
| RIDADR | UN 2811 |
| RTECS | YR8450000 |
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| cs-439 |
| urea, N'-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitroso-, hydrochloride (1:1) |
| nimustine monohydrochloride |
| 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride (1:1) |
| 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-1-(2-chloroethyl)-1-nitroso-ure |
| Nimustine HCL |
| 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride |
| MFCD01676942 |
| N'-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea hydrochloride |
| 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chlorethyl)-1-nitrosoharnstoffhydrochlorid |
| nimustinaclorhidrato |
| 1-(4-Amino-2-methyl-5-pyrimidinyl)-1-methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride |
| 1-((4-amino-2-methyl-5-pyrimidinyl)methyl)-3-(2-chloroethyl)-3-nitrosoure hydrochloride |
| ACNU |
| 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride (1:1) |
| Nimustine Hydrochloride |
| nidran |
| 4-amino-5-({[N-(2-chloroethyl)-N-nitrosocarbamoyl]amino}methyl)-2-methylpyrimidin-1-ium chloride |