heptaethylene glycol

Modify Date: 2024-01-04 23:54:58

heptaethylene glycol Structure
heptaethylene glycol structure
Common Name heptaethylene glycol
CAS Number 5617-32-3 Molecular Weight 326.383
Density 1.1±0.1 g/cm3 Boiling Point 435.0±40.0 °C at 760 mmHg
Molecular Formula C14H30O8 Melting Point N/A
MSDS N/A Flash Point 216.9±27.3 °C

 Use of heptaethylene glycol


Heptaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name heptaethylene glycol
Synonym More Synonyms

 heptaethylene glycol Biological Activity

Description Heptaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 435.0±40.0 °C at 760 mmHg
Molecular Formula C14H30O8
Molecular Weight 326.383
Flash Point 216.9±27.3 °C
Exact Mass 326.194061
PSA 95.84000
LogP -3.30
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.462

 Safety Information

HS Code 2909499000

 Synthetic Route

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

Heptaethylene Glycol
3,6,9,12,15,18-Hexaoxaicosane-1,20-diol
3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol
EINECS 227-040-3
2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
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