Bis-Tos-PEG7

Modify Date: 2024-01-09 15:56:31

Bis-Tos-PEG7 Structure
Bis-Tos-PEG7 structure
 Common Name Bis-Tos-PEG7
CAS Number 69502-27-8 Molecular Weight 634.75600
Density N/A Boiling Point N/A
Molecular Formula C28H42O12S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-Tos-PEG7


Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Synonym More Synonyms

 Bis-Tos-PEG7 Biological Activity

Description Bis-Tos-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C28H42O12S2
Molecular Weight 634.75600
Exact Mass 634.21200
PSA 158.88000
LogP 4.67540

 Safety Information

Hazard Codes Xn

 Synonyms

heptaethylene glycol ditosylate
2-[2-(2-{2-[2-(2-{2-[(4-methylphenyl)sulfonyloxy]ethoxy}ethoxy)ethoxy]ethoxy}e thoxy)ethoxy]ethyl 4-methylbenzenesulfonate
3,6,9,12,15,18-Hexaoxaicosane-1,20-diyl bis(4-methylbenzenesulfonate)
1,20-bis(tosyloxy)-3,6,9,12,15,18-hexaoxaeicosane
Heptaethylene glycol di(p-toluenesulfonate)
3,6,9,12,15,18-hexaoxaeicosane-1,20-diol ditosylate
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Chemsrc provides Bis-Tos-PEG7(CAS#:69502-27-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Bis-Tos-PEG7 are included as well.>> amp version: Bis-Tos-PEG7

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