Tos-PEG5-Boc

Modify Date: 2024-01-14 10:27:25

Tos-PEG5-Boc Structure
Tos-PEG5-Boc structure
Common Name Tos-PEG5-Boc
CAS Number 581065-94-3 Molecular Weight 476.58100
Density N/A Boiling Point N/A
Molecular Formula C22H36O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG5-Boc


Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 16-(p-toluenesulfonyl)-4,7,10,13,16-pentaoxahexadecanoic acid tert-butyl ester
Synonym More Synonyms

 Tos-PEG5-Boc Biological Activity

Description Tos-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

 Chemical & Physical Properties

Molecular Formula C22H36O9S
Molecular Weight 476.58100
Exact Mass 476.20800
PSA 114.97000
LogP 3.57930

 Precursor & DownStream

Precursor  0

DownStream  2

 Synonyms

MFCD22574810
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