Tos-PEG5-C2-Boc

Modify Date: 2024-01-02 16:54:17

Tos-PEG5-C2-Boc Structure
Tos-PEG5-C2-Boc structure
Common Name Tos-PEG5-C2-Boc
CAS Number 850090-10-7 Molecular Weight 520.633
Density 1.1±0.1 g/cm3 Boiling Point 591.4±50.0 °C at 760 mmHg
Molecular Formula C24H40O10S Melting Point N/A
MSDS N/A Flash Point 311.4±30.1 °C

 Use of Tos-PEG5-C2-Boc


Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15-pentaoxaoctadecan-18-oate
Synonym More Synonyms

 Tos-PEG5-C2-Boc Biological Activity

Description Tos-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 591.4±50.0 °C at 760 mmHg
Molecular Formula C24H40O10S
Molecular Weight 520.633
Flash Point 311.4±30.1 °C
Exact Mass 520.234192
LogP 1.37
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.491

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD22683305
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 1-{[(4-methylphenyl)sulfonyl]oxy}-3,6,9,12,15-pentaoxaoctadecan-18-oate
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