NSC 207895
Modify Date: 2024-01-09 17:26:19
NSC 207895 structure
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Common Name | NSC 207895 | ||
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| CAS Number | 58131-57-0 | Molecular Weight | 279.252 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 487.6±55.0 °C at 760 mmHg | |
| Molecular Formula | C11H13N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 248.7±31.5 °C | |
Use of NSC 207895NSC-207895 (XI-006), a DNA damaging agent, is an anticancer agent and p53 activator[1][2][3]. |
| Name | 4-(4-methylpiperazin-1-yl)-7-nitro-3-oxido-2,1,3-benzoxadiazol-3-ium |
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| Synonym | More Synonyms |
| Description | NSC-207895 (XI-006), a DNA damaging agent, is an anticancer agent and p53 activator[1][2][3]. |
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| Related Catalog | |
| In Vitro | NSC-207895 (0.5 μM, 30 min), a MDM2 inhibitor, upregulates p53 protein levels[2]. NSC-207895, MDMX inhibitor, downregulates the expression of MDMX in AML cells at the mRNA and protein levels[3]. Western Blot Analysis[2] Cell Line: RAW 264.7 cells. Concentration: 0.5 μM. Incubation Time: 30 min (stimulated with LPS (100 ng/ml) for 6 h). Result: Upregulated p53 protein levels. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 487.6±55.0 °C at 760 mmHg |
| Molecular Formula | C11H13N5O4 |
| Molecular Weight | 279.252 |
| Flash Point | 248.7±31.5 °C |
| Exact Mass | 279.096741 |
| PSA | 103.79000 |
| LogP | 1.46 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.738 |
| Storage condition | -20℃ |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA
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| 7-(4-Methyl-1-piperazinyl)-4-nitrobenzofurazan 1-oxide |
| Benzofurazan,4-(4-methyl-1-piperazinyl)-7-nitro-,3-oxide |
| 7-(4-Methyl-1-piperazinyl)-4-nitro-2,1,3-benzoxadiazole 1-oxide |
| B2368 |
| 2,1,3-Benzoxadiazole, 7-(4-methyl-1-piperazinyl)-4-nitro-, 1-oxide |
| 7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole 1-oxide |